Measuring enzymatic kinetics for over 200,000 substrates with mRNA display 
De novo discovery of natural product-like peptides with bioactivities of interest 
mRNA display + deep learning for PTM enzyme profiling 
De novo discovery of natural product-like peptides with bioactivities of interest 
AI-guided design of combinatorial libraries of natural product-like peptides 
mRNA display + deep learning for PTM enzyme profiling 
Selective late-stage modification of peptides
We are a young research group at National University of Singapore, located in the Department of Pharmacy and Pharmaceutical Sciences. The lab has opened its doors on the 6th floor of NUS S9 Wet Science Building in December 2024.
We are interested in solving major problems at the intersection of chemistry and biology using the tools of chemical biology, enzymology, drug discovery, and deep learning/AI. Check out the summary of our research and publications to learn more.
Currently, we are actively hiring at multiple levels: check the join us page for more info.
Vinogradov Group 